Semax + Selank

Semax and Selank are synthetic peptides studied for their complementary effects on brain function, combining Semax’s neuroprotective and cognitive-enhancing properties with Selank’s anxiolytic and mood-stabilizing effects. Together, they are explored for supporting focus, memory, stress reduction, and overall cognitive performance without significant sedation.

This blend contains

Semax

Semax is a synthetic peptide studied for its neuroprotective and nootropic effects, potentially supporting memory, focus, and brain recovery by boosting BDNF and enhancing neural plasticity.

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Selank

Selank is a synthetic peptide studied for its ability to reduce anxiety, enhance cognitive function, and support immune regulation without the sedation or dependency risks of traditional anxiolytics.

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Research Highlights

Research on

Semax

Neuroprotective Effects & Memory Enhancement in Alcohol Models

In rodent studies where chronic ethanol caused memory impairment, Selank improved cognitive performance and mitigated reductions in BDNF in the hippocampus and frontal cortex.

Source: Springer

Gene Expression Modulation in Stress and Immunity

Selank alters the expression of over 30 genes related to inflammation—such as cytokines, chemokines, their receptors, and immune development regulators like Bcl6—under social stress conditions in mice.

Source: ResearchGate

Immune Modulation of Pro-inflammatory Cytokines During Stress

In a social stress model, Selank significantly reduced stress-induced elevations in IL‑1β, IL‑6, TNF‑α, and TGF‑β1, while helping restore levels of anti-inflammatory IL‑4.

Source: Dr. D. F. Aleksandrovna, 2020

Neurotransmitter Regulation & BDNF Expression

Selank’s pharmacological profile includes modulation of GABAergic, serotonergic, and dopaminergic systems, alongside rapid induction of hippocampal BDNF expression, supporting both anxiolytic and neuroplastic effects.

Source: pep-pedia

Research on

Selank

Regulates Neurotransmiters and Enhances BDNF Expression

Selank modulates the balance of monoamines such as GABA, serotonin, and dopamine, and has been shown to increase BDNF expression in the rat hippocampus—supporting mood and neuroplasticity.

Source: wikipedia

Inhibits Enkephalin-Degrading Enzymes for Anxiolytic Effects

Selank inhibits enzymes that degrade enkephalins, thereby enhancing endogenous calming peptides and reducing anxiety-like behavior in animal models.

Source: wikipedia

Supports Stress Resilience & Cognitive Function

In rodent models of chronic stress, Selank alleviated depression-like behavior and improved memory and cognitive performance.

Source: peptidesource

Immune System Modulation & Anti-inflammatory Effects

Selank influences cytokine expression—such as IL‑6—and regulatory genes tied to immune function, suggesting both immunomodulatory and neuroprotective properties.

Source: wikpedia